Metrizamide
Based on 1 Customer Validation
Metrizamide (Amipaque) is used as the contrast medium for angiography in neuroradiological investigations. Metrizamide inhibits human brain hexokinase.
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- Purity: 99.0%
- CAS No.: 31112-62-6
- 화학식: C18H22I3N3O8
- 분자량:789.10
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
Metrizamide is a contrast medium possessing unique properties, one of which is that even in an isotonic solution it has a radiographic density sufficient for a diagnostic myelogram[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 31112-62-6
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Appearance Solid
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분자량 789.10
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화학식 C18H22I3N3O8
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Color White to off-white
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SMILES
IC(C(N(C)C(C)=O)=C1I)=C(C(N[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)OC2O)=O)C(I)=C1NC(C)=O
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Synonyms
Amipaque
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : ≥ 50 mg/mL (63.36 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (276 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Vogelsang H, et al. Zerebrale und spinale Angiographie mit Metrizamid (Amipaque) [Cerebral and spinal angiography with metrizamide (amipaque) (author's transl)]. Rofo. 1978;129(5):559-561. [Content Brief]
[2]. Bertoni JM. Metrizamide inhibits human brain hexokinase. Neurology. 1982;32(8):884-887. [Content Brief]
[3]. Funkquist B. Myelographic localization of spinal cord compression in dogs. A comparison between cisternal and lumbar injections of metrizamide "Amipaque" in diagnosing and locating spinal cord compression. Acta Vet Scand. 1975;16(2):269-287. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2673 mL | 6.3363 mL | 12.6727 mL | 31.6817 mL |
| 5 mM | 0.2535 mL | 1.2673 mL | 2.5345 mL | 6.3363 mL | |
| 10 mM | 0.1267 mL | 0.6336 mL | 1.2673 mL | 3.1682 mL | |
| 15 mM | 0.0845 mL | 0.4224 mL | 0.8448 mL | 2.1121 mL | |
| 20 mM | 0.0634 mL | 0.3168 mL | 0.6336 mL | 1.5841 mL | |
| 25 mM | 0.0507 mL | 0.2535 mL | 0.5069 mL | 1.2673 mL | |
| 30 mM | 0.0422 mL | 0.2112 mL | 0.4224 mL | 1.0561 mL | |
| 40 mM | 0.0317 mL | 0.1584 mL | 0.3168 mL | 0.7920 mL | |
| 50 mM | 0.0253 mL | 0.1267 mL | 0.2535 mL | 0.6336 mL | |
| 60 mM | 0.0211 mL | 0.1056 mL | 0.2112 mL | 0.5280 mL |
Metrizamide Related Classifications
HY-W000133 Related Classifications
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