Mito-Rh-S
Based on 1 Customer Validation
Mito-Rh-S is a ratiometric near-infrared (NIR) fluorescent probe that detects the fluctuation of mitochondrial HClO levels during ferroptosis in hepatocellular carcinoma (HCC).
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- Purity: 97.03%
- 화학식: C40H39ClN2O8S
- 분자량:743.26
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보관:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
Mito-Rh-S has an ultrafast response rate (2s) and large emission shift (115 nm). Mito-Rh-S has a high signal-to-noise ratio[1].
The cell experiments of Mito-Rh-S demonstrated that Fe2+- and Erastin-induced ferroptosis in HepG2 cells resulted in elevated levels of mitochondrial HClO[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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분자량 743.26
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화학식 C40H39ClN2O8S
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Color Blue to dark blue
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SMILES
O=Cl(=O)([O-])=O.CCN1C(C=CC=C2)=C2SC(C=C3/C=C4C5=[O+]C6=CC(N(CC)CC)=CC=C6C(C7=C(C(O)=O)C=CC=C7)=C5CCC/4)=C1C=C3OC
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
용액&용해도
DMSO : 20 mg/mL (26.91 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3454 mL | 6.7271 mL | 13.4542 mL | 33.6356 mL |
| 5 mM | 0.2691 mL | 1.3454 mL | 2.6908 mL | 6.7271 mL | |
| 10 mM | 0.1345 mL | 0.6727 mL | 1.3454 mL | 3.3636 mL | |
| 15 mM | 0.0897 mL | 0.4485 mL | 0.8969 mL | 2.2424 mL | |
| 20 mM | 0.0673 mL | 0.3364 mL | 0.6727 mL | 1.6818 mL | |
| 25 mM | 0.0538 mL | 0.2691 mL | 0.5382 mL | 1.3454 mL |
Mito-Rh-S Related Classifications
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