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Cat. No.: HY-106951

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MK 386

(Synonyms: L-733692)

MK 386 (L-733692) is a selective 5-α-reductase I inhibitor, used for prostate cancer inhibition.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 158493-17-5
화학식: C₂₈H₄₉NO
분자량:415.69

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

MK 386 Chemical Structure

CAS No.: 158493-17-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

MK 386 (L-733692) is a selective 5-α-reductase I inhibitor, used for prostate cancer inhibition^[1].

IC₅₀ & Target

5-α-reductase I^[1]

In Vitro

MK 386 (5 μM; 48 h) modulates the mRNA level of related genes, in LNCaP cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 158493-17-5
분자량 415.69
화학식 C₂₈H₄₉NO
SMILES

C[C@@]12[C@]3([H])[C@]([C@@H](C)C[C@@]1([H])N(C(CC2)=O)C)([H])[C@@]4([H])[C@@](C)([C@]([C@H](C)CCCC(C)C)([H])CC4)CC3
Synonyms

L-733692
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bühler P, et al. Comparison of gene expression in LNCaP prostate cancer cells after treatment with bicalutamide or 5-alpha-reductase inhibitors. Urol Int. 2010;84(2):203-11. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

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Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

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MK 386

Epristeride

Finasteride

Stigmasterol glucoside

Dutasteride

12-O-Methylcarnosic acid

Epristeride (Standard)

Alpha-Estradiol-d2

Finasteride (Standard)

12-O-Methylcarnosic acid (Standard)

Finasteride acetate

CGP-53153

Dutasteride (Standard)

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

MK 386

Epristeride

Finasteride

Stigmasterol glucoside

Dutasteride

12-O-Methylcarnosic acid

Epristeride (Standard)

Alpha-Estradiol-d2

Finasteride (Standard)

12-O-Methylcarnosic acid (Standard)

Finasteride acetate

CGP-53153

Dutasteride (Standard)

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

MK 386 Related Classifications

HY-106951 Related Classifications