Mps-BAY1
Mps-BAY1 is an MPS1 inhibitor with anticancer activity. Mps-BAY1 inhibits cell proliferation and induces apoptosis by activating mitotic catastrophe in cancer cells, generating global aneuploidy and polyploidy. Mps-BAY1 can be used in the study of colorectal cancer and cervical cancer.
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- CAS No.: 1309593-24-5
- 화학식: C27H20N6O
- 분자량:444.49
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
695 nM
Compound: 27
|
Antiproliferative activity against human HeLa cells after 96 hrs by crystal violet staining based assay
Antiproliferative activity against human HeLa cells after 96 hrs by crystal violet staining based assay
|
[PMID: 32338514] |
Chemical Information
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CAS No. 1309593-24-5
-
분자량 444.49
-
화학식 C27H20N6O
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SMILES
N#CC1=C(NC2=NN3C=C(C4=CC=C(NC(CC5=CC=CC=C5)=O)C=C4)C=CC3=N2)C=CC=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)