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Cat. No.: HY-126332

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NED-3238

NED-3238 is a highly potent arginase I and II inhibitor with IC₅₀ values of 1.3 nM and 8.1 nM, respectively.

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CAS No.: 2389062-09-1
화학식: C₁₇H₂₈BN₃O₄
분자량:349.23

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

NED-3238 Chemical Structure

CAS No.: 2389062-09-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

NED-3238 is a highly potent arginase I and II inhibitor with IC₅₀ values of 1.3 nM and 8.1 nM, respectively^[1].

IC₅₀ & Target

IC50: 1.3 nM (arginase I) and 8.1 nM (arginase II)^[1]

Chemical Information

CAS No. 2389062-09-1
분자량 349.23
화학식 C₁₇H₂₈BN₃O₄
SMILES

O=C([C@]1(N)CN(C[C@@H](N)CC2=CC=CC=C2)C[C@@H]1CCCB(O)O)O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Van Zandt MC, et al. Discovery of N-Substituted 3-Amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic Acids as Highly Potent Third-Generation Inhibitors of Human Arginase I and II. J Med Chem. 2019 Aug 23. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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