Nidulin
Nidulin (Methylustin) is a depsidone isolated from a marine fungus Aspergillus unguis. Nidulin shows antifungal and antibacterial against pathogenetic strains, Pseudomonas aeruginosa, Methicillin-resistant Staphylococcus aureus and Candida albicans with inhibition zones of 9.5 mm, 9.0 mm and 9.0 mm, respectively. Nidulin exhibits potent larvicidality against brine shrimp.
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- CAS No.: 10089-10-8
- 화학식: C20H17Cl3O5
- 분자량:443.70
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Vero | IC50 |
4.6 μg/mL
Compound: 12
|
Cytotoxicity against African green monkey Vero cells by colorimetric assay
Cytotoxicity against African green monkey Vero cells by colorimetric assay
|
[PMID: 33861594] |
| Vero | IC50 |
57 μg/mL
Compound: 12
|
Cytotoxicity against African green monkey Vero cells incubated for 24 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells incubated for 24 hrs by MTT assay
|
[PMID: 33861594] |
Chemical Information
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CAS No. 10089-10-8
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분자량 443.70
-
화학식 C20H17Cl3O5
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SMILES
O=C1C2=C(C)C(Cl)=C(O)C(Cl)=C2OC3=C(/C(C)=C/C)C(Cl)=C(OC)C(C)=C3O1
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Synonyms
Methylustin
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Structure Classification
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Initial Source
Aspergillus unguis
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)