NS2359
NS2359 (GSK372475) is a serotonin-norepinephrine-dopamine triple reuptake inhibitor. NS2359 is used for research on depression.
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- CAS No.: 195875-68-4
- 화학식: C16H21Cl2NO
- 분자량:314.25
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
NS2359 simultaneously blocks three monoamine transporters and increases the levels of three types of neurotransmitters in the synaptic cleft to regulate mood, cognition and reward pathways.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 195875-68-4
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분자량 314.25
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화학식 C16H21Cl2NO
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SMILES
COC[C@@H]1[C@@H](C2=CC(Cl)=C(C=C2)Cl)C[C@@]3([H])N([C@]1([H])CC3)C
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Synonyms
GSK372475
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Learned S, et al. Efficacy, safety, and tolerability of a triple reuptake inhibitor GSK372475 in the treatment of patients with major depressive disorder: two randomized, placebo- and active-controlled clinical trials. Journal of psychopharmacology (Oxford, England). 2012 May;26(5):653-62. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)