Parawixin10
Parawixin10 (Compound 2) is an N-acylpolyamine. Parawixin10 fails to enhance glutamate uptake in radioligand uptake assays of EAAT1, EAAT2 or EAAT3. Parawixin10 exhibits no positive allosteric modulatory activity in radioligand uptake assays of EAAT1−EAAT3, nor can it improve neuronal survival rates in mice in a dose-dependent and statistically significant manner. Parawixin10 has no neuroprotective activity.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C30H55I2N9O3
- 분자량:843.63
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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EAAT1 |
EAAT2 |
EAAT3 |
Chemical Information
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분자량 843.63
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화학식 C30H55I2N9O3
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SMILES
C[N+](C)(CCCC[N+](C)(C)CCCNC(CC1=CNC2=CC=CC(O)=C21)=O)CCCNC([C@H](CCCNC(N)=N)N)=O.[I-].[I-]
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Doroudian Y, et al. The N-Acylpolyamine Structure Assigned as Parawixin10 Does Not Display Positive Allosteric Modulatory Activity in EAAT1-3 Radioligand Uptake Assays, nor Does It Enhance Neuronal Survival in Mice in a Dose-Dependent and Statistically Significant Way. ACS Chem Neurosci. 2026;17(8):1530-1539. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)