PB01
PB01 is a DPP-4 inhibitor with an IC50 of 15.66 nM. It effectively inhibits high glucose-induced ROS production and mitochondrial superoxide formation while significantly reducing cellular DPP-4 expression. PB01 can also significantly lower blood glucose levels in diabetic mice. Additionally, PB01 demonstrates good safety, exhibiting almost no cytotoxicity at a concentration of 100 μM. PB01 holds potential for research in the field of diabetes.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 368434-78-0
- 화학식: C18H21N5O3
- 분자량:355.39
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
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Help & FAQs
Biological Activity
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DPP-4 15.66 nM (IC50) |
Chemical Information
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CAS No. 368434-78-0
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분자량 355.39
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화학식 C18H21N5O3
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SMILES
O=C1C2=C(N(C)C(N1C)=O)N=C(N3CCOCC3)N2CC4=CC=CC=C4
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PB01 Related Classifications
HY-170572 Related Classifications
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