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United States

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Cat. No.: HY-133908

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PFI-3 Control

PFI-3 Control is an inactive analog of PFI-3 (HY-12409), serving as an inactive negative control. PFI-3 Control shows no detectable binding activity toward purified PB1 (5), SMARCA2A, SMARCA2B, and SMARCA4 family VIII bromodomain proteins.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1914047-60-1
화학식: C₂₂H₂₃N₅O₃
분자량:405.45

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

PFI-3 Control Chemical Structure

CAS No.: 1914047-60-1

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All SWI/SNF Complex Isoforms :

In Vitro

PFI-3 Control (Compound 18) (100 nM-1 μM) fails to displace GFP-tagged PB1 from chromatin in SAHA (HY-10221)-treated U2OS cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1914047-60-1
분자량 405.45
화학식 C₂₂H₂₃N₅O₃
SMILES

O=C(C1=CC=CC(OC)=C1O)/C=C/N2[C@@](C3)([H])CN(C4=NC=CC(NCC#C)=N4)[C@@]3([H])C2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Gerstenberger BS, et al. Identification of a Chemical Probe for Family VIII Bromodomains through Optimization of a Fragment Hit. Journal of medicinal chemistry. 2016 May 26;59(10):4800-11. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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