country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-137063

Copy Link Print Information

(+)-ITD-1

(+)-ITD-1 is an inhibitor for TGF-β, that inhibits the TGF-β2 with an IC₅₀ of 0.46 μM. (+)-ITD-1 promotes the degradation of TGF-b type II receptor (TGFBR2) and the differentiation of cardiomyocyte, and inhibits the mesoderm formation in the early differentiation stage of mouse embryonic stem cells (mESCs).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1409968-46-2
화학식: C₂₇H₂₉NO₃
분자량:415.52

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

(+)-ITD-1 Chemical Structure

CAS No.: 1409968-46-2

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All TGF-beta/Smad Isoforms :

Smad1
Smad3

All TGF-β Receptor Isoforms :

Chemical Information

CAS No. 1409968-46-2
분자량 415.52
화학식 C₂₇H₂₉NO₃
SMILES

O=C(C([C@H](C1=CC=C(C2=CC=CC=C2)C=C1)C(C(C3)=O)=C(CC3(C)C)N4)=C4C)OCC
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Willems E, et al., Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells. Cell Stem Cell. 2012 Aug 3;11(2):242-52. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

견적 받기 해외재고보유

Other size

견적 받기

Amount: USD 0.00

Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

(+)-ITD-1

SB-431542

Pirfenidone

SB-431542 (GMP)

SIS3

LY2109761

LDN193189 Tetrahydrochloride

SB-431542 (Standard)

SRI-011381 hydrochloride

Pirfenidone (Standard)

EMT inhibitor-1

LY2109761 (Standard)

EMT inhibitor-1 (Standard)

All TGF-beta/Smad Isoforms

All TGF-β Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Bioz

(+)-ITD-1

SB-431542

Pirfenidone

SB-431542 (GMP)

SIS3

LY2109761

LDN193189 Tetrahydrochloride

SB-431542 (Standard)

SRI-011381 hydrochloride

Pirfenidone (Standard)

EMT inhibitor-1

LY2109761 (Standard)

EMT inhibitor-1 (Standard)

All TGF-beta/Smad Isoforms

All TGF-β Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

(+)-ITD-1 Related Classifications

HY-137063 Related Classifications

Bioz