EphB6
EphB6 is the singular kinase-deficient member of the Eph family: its intracellular region lacks several tyrosine residues essential for catalysis, yet the receptor remains biologically active, transmitting signals by recruiting adaptor and effector proteins and by heterodimerizing with catalytically competent Eph receptors to modulate their output. EphB6 is expressed predominantly in lymphoid tissues, intestine and placenta. It behaves as a negative regulator of cell migration and adhesion, functions as a tumor suppressor that is silenced or lost in metastatic melanoma, breast and colorectal cancers, and has been implicated in T-cell signaling and inflammatory bowel disease. Recombinant EphB6 supports these mechanistic studies.
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EphB6 Recombinant Proteins (5)
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- 화학식: Human
- 분자량: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
