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Cat. No.: HY-186166

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(S)-Embibatinib

(Synonyms: (S)-TERN-701)

(S)-Embibatinib ((S)-TERN-701), an isomer of TERN-701 (HY-182792), is a selective BCR-ABL allosteric inhibitor. (S)-Embibatinib can be usd for the research of cancer.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2412969-12-9
화학식: C₂₃H₁₈ClF₄N₅O₃
분자량:523.87

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

(S)-Embibatinib Chemical Structure

CAS No.: 2412969-12-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
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Bioz

Biological Activity

제품 설명

(S)-Embibatinib ((S)-TERN-701), an isomer of TERN-701 (HY-182792), is a selective BCR-ABL allosteric inhibitor. (S)-Embibatinib can be usd for the research of cancer^[1].

All Bcr-Abl Isoforms :

Abl
Bcr-Abl

In Vitro

(S)-Embibatinib (Compound 231) shows CC₅₀ of 13.52 nM for Abl K562 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2412969-12-9
분자량 523.87
화학식 C₂₃H₁₈ClF₄N₅O₃
SMILES

C[C@@H](CO)N1C(C(F)F)=NC2=C1C(C3=CN=CN=C3)=CC(C(NC4=CC=C(OC(Cl)(F)F)C=C4)=O)=C2
Synonyms

(S)-TERN-701
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. F. Anthony Romero, et al. Compounds for treating certain leukemias. WO2020061086A2. 2021-03-18

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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(S)-Embibatinib

All Bcr-Abl Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

(S)-Embibatinib Related Classifications

HY-186166 Related Classifications