(S)-Subasumstat
Based on 1 Customer Validation
(S)-Subasumstat is the isomer of Subasumstat (HY-111789). Subasumstat (TAK-981) is a first in class and selective inhibitor of the SUMOylation enzymatic cascade, with potential immune-activating and antineoplastic activities.
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- Purity: 98.39%
- CAS No.: 1858282-76-4
- 화학식: C25H28ClN5O5S2
- 분자량:578.10
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 1858282-76-4
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Appearance Solid
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분자량 578.10
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화학식 C25H28ClN5O5S2
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Color White to light yellow
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SMILES
O=S(OC[C@@H]1[C@@H](O)C[C@H](NC2=NC=NC=C2C(C3=CC([C@H]4NCCC5=C4C=C(Cl)C=C5)=C(C)S3)=O)C1)(N)=O
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Synonyms
(S)-TAK-981
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 100 mg/mL (172.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (272 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
[1]. Sumoylation inhibitor TAK-981.
[2]. TAK-981.
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7298 mL | 8.6490 mL | 17.2980 mL | 43.2451 mL |
| 5 mM | 0.3460 mL | 1.7298 mL | 3.4596 mL | 8.6490 mL | |
| 10 mM | 0.1730 mL | 0.8649 mL | 1.7298 mL | 4.3245 mL | |
| 15 mM | 0.1153 mL | 0.5766 mL | 1.1532 mL | 2.8830 mL | |
| 20 mM | 0.0865 mL | 0.4325 mL | 0.8649 mL | 2.1623 mL | |
| 25 mM | 0.0692 mL | 0.3460 mL | 0.6919 mL | 1.7298 mL | |
| 30 mM | 0.0577 mL | 0.2883 mL | 0.5766 mL | 1.4415 mL | |
| 40 mM | 0.0432 mL | 0.2162 mL | 0.4325 mL | 1.0811 mL | |
| 50 mM | 0.0346 mL | 0.1730 mL | 0.3460 mL | 0.8649 mL | |
| 60 mM | 0.0288 mL | 0.1442 mL | 0.2883 mL | 0.7208 mL | |
| 80 mM | 0.0216 mL | 0.1081 mL | 0.2162 mL | 0.5406 mL | |
| 100 mM | 0.0173 mL | 0.0865 mL | 0.1730 mL | 0.4325 mL |
(S)-Subasumstat Related Classifications
HY-111789A Related Classifications
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