SA1103064
SA1103064 is a potent antibiotic with antibacterial activity against multiple resistant bacterial strains. SA1103064 binds to the bacterial ribosome's nascent peptide exit tunnel. SA1103064 can be used for the research of bacterial infections.
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- 화학식: C39H50FN7O6
- 분자량:731.86
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Antibiotic Isoforms
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Biological Activity
제품 설명
In Vitro
SA1103064 (compound 48a) binds to the E. coli ribosome's nascent peptide exit tunnel, forming π-stacking interactions with U1782-U2586 and van der Waals interactions with U2585, occupying the site of tetracenomycin X and mimicking VS1 binding contacts[1].
SA1103064 exhibits potent antibacterial activity against multiple Gram-positive strains, including drug-resistant isolates, with MIC values ranging from 1 to 8 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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분자량 731.86
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화학식 C39H50FN7O6
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SMILES
[H][C@]12CCCN1C(C3=COC(C[C@@H](C[C@@H](/C=C(/C=C/CNC(/C=C/[C@H]([C@H](OC2=O)C(C)C)CCCCCN4C=C(N=N4)C5=CC=NC=C5)=O)C)O)F)=N3)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- SA1103064
- SA 1103064
- SA-1103064
- Antibiotic
- Bacterial
- VatA/Vgb-resistant Staphylococcus aureus
- U2585
- bacterial infections
- Gram-positive strains
- bacterial ribosome
- U1782-U2586
- nascent peptide exit tunnel
- multidrug-resistant bacterial infections
- E. coli ribosome
- ErmC-resistant Staphylococcus aureus
- Inhibitor
- inhibitor
- inhibit