Copy Link Print Information

Sacituzumab

(Synonyms: HRS7; hRS7)
9 Cited Publications
고객리뷰

Based on 9 publication(s) in Google Scholar

Sacituzumab is a humanized IgG1 monoclonal antibody targeting Trophoblast cell surface antigen 2 (TROP2). Sacituzumab demonstrates a lack of antitumor effects alone and does not inhibit the function of TROP-2 during tumor metastasis, binding to the linear epitopes of TROP-2 protein. Sacituzumab can be used for the synthesis of antibody-drug conjugates (ADC) drug Sacituzumab govitecan (HY-132254). Sacituzumab govitecan can be used in the field of triple-negative breast cancer.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Sacituzumab
  • Experimental Validation Results for Sacituzumab
  • Experimental Validation Results for Sacituzumab
  • Experimental Validation Results for Sacituzumab
  • Sacituzumab Chemical Structure
    Sacituzumab Chemical Structure
CAS No.: 1796566-95-4
사이즈
가격
재고
수량
Amount: USD 0.00
Please select quantity
or
or

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of Sacituzumab:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
주변의 대리점 찾기 Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • 순도&문서
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) Sacituzumab

More
Keywords
MOQ
Minimum order quantity
100 mg

견적 받기 해외재고보유

Other size
견적 받기
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress 로그인
Register
Sign in to MedChemExpress
회원가입

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Loaded Sacituzumab on AHC2 biosensor, can bind TROP-2 Protein, Human (248a.a, HEK293, His, HY-P70457) with an affinity constant of 8.077E-10 M as determined in BLI assay.

  • 1/16

    Flow cytometry analysis of Trop2 overexpression HEK293 cells labelling Trop2 with Sacituzumab at 67nM (Red). Goat anti human IgG Fc (Alexa Fluor488) was used as the secondary antibody at 1/400 dilution. Isotype control - human IgG (Blue). Unlabeled control - Unlabelled cells (Gray).

  • 1/16

    Immobilized TROP-2 Protein, Human (HY-P70457) can bind Sacituzumab, with the EC50 is 1.335 ng/mL.

  • Sacituzumab Chemical Structure
    1/16
  • Sacituzumab
  • Loaded Sacituzumab on AHC2 biosensor, can bind TROP-2 Protein, Human (248a.a, HEK293, His, HY-P70457) with an affinity constant of 8.077E-10 M as determined in BLI assay.
  • Flow cytometry analysis of Trop2 overexpression HEK293 cells labelling Trop2 with Sacituzumab at 67nM (Red). Goat anti human IgG Fc (Alexa Fluor488) was used as the secondary antibody at 1/400 dilution. Isotype control - human IgG (Blue). Unlabeled control - Unlabelled cells (Gray).
  • Immobilized TROP-2 Protein, Human (HY-P70457) can bind Sacituzumab, with the EC50 is 1.335 ng/mL.