Scillascillin
Scillascillin (compound 10) is a homoisoflavanone. Scillascillin can be isolated from S. scilloides. Scillascillin shows anticancer activity towards MCF-7 (breast cancer) and DU-145 (prostate cancer) cells with the IC50 of 9.59 and 11.32 ug/ml, respectively.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 52706-07-7
- 화학식: C17H12O6
- 분자량:312.27
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HUVEC | GI50 |
>100 μM
Compound: 15
|
Antiproliferative activity against HUVEC assessed as reduction in cell number incubated for 44 hrs by alamar blue based fluorescence assay
Antiproliferative activity against HUVEC assessed as reduction in cell number incubated for 44 hrs by alamar blue based fluorescence assay
|
[PMID: 30951308] |
| Y79 | GI50 |
>100 μM
Compound: 15
|
Cytotoxicity against human Y79 cells assessed as reduction in cell number incubated for 44 hrs by alamar blue based fluorescence assay
Cytotoxicity against human Y79 cells assessed as reduction in cell number incubated for 44 hrs by alamar blue based fluorescence assay
|
[PMID: 30951308] |
Chemical Information
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CAS No. 52706-07-7
-
분자량 312.27
-
화학식 C17H12O6
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SMILES
O=C1[C@]2(C3=C(C2)C=C(OCO4)C4=C3)COC5=CC(O)=CC(O)=C15
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Structure Classification
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Yoichiro Nishida, et al. A new homostilbene and two new homoisoflavones from the bulbs of Scilla scilloides. Chem Pharm Bull (Tokyo). 56, 7. [Content Brief]
[2]. Chinthala Y, et al. Anticancer Active Homoisoflavone from the Underground Bulbs of Ledebouria hyderabadensis. Pharmacognosy Res. 2014;6(4):303-305. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)