Scio-323

Scio-323 is an orally available p38 mitogen-activated protein kinase (MAPK) inhibitor with the potential to inhibit chronic inflammatory responses associated with polyethylene particles. Scio-323's oral inhibition pattern had a minimal effect on bone formation. Scio-323 administration inhibited net bone formation after the establishment of a chronic inflammatory response to polyethylene particles. Osteoblast-like activity remained low in all cases of Scio-323 inhibition. Scio-323 failed to improve bone growth in the presence of polyethylene particles.

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  • CAS No.: 309913-51-7
  • 화학식: C27H30FN3O4
  • 분자량:479.54
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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