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United States

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Cat. No.: HY-164536

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SLCB050

SLCB050 is a compound that blocks the interaction between DX2 and p14/ARF and has anticancer activity. SLCB050 reduces the viability of human lung cancer cells, especially small cell lung cancer cells, in a p14/ARF-dependent manner and induces apoptosis and senescence.

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CAS No.: 1848971-16-3
화학식: C₂₁H₁₈O₆
분자량:366.36

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

SLCB050 Chemical Structure

CAS No.: 1848971-16-3

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Cellular Effect

Cell Line	Type	Value	Description	References
NSCLC	GI₅₀	>50 μM Compound: SLCB050	Growth inhibition of human NSCLC Growth inhibition of human NSCLC	[PMID: 32208684]
SCLC	GI₅₀	5 μM Compound: SLCB050	Inhibition of DX2-p14/ARF interaction in human SCLC cells assessed as inhibition of cell growth by MTT assay Inhibition of DX2-p14/ARF interaction in human SCLC cells assessed as inhibition of cell growth by MTT assay	[PMID: 32208684]

Chemical Information

CAS No. 1848971-16-3
분자량 366.36
화학식 C₂₁H₁₈O₆
SMILES

CC1(OC2=CC(OC(C=C3)=O)=C3C=C2C[C@@H]1OC(/C=C/C4=CC=CO4)=O)C
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ah-Young, et al. "Inhibiting DX2-p14/ARF interaction exerts antitumor effects in lung cancer and delays tumor progression." Cancer Research 76.16 (2016): 4791-4804. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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