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Cat. No.: HY-19138

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SR 47063

SR 47063 is an ATP-sensitive potassium channel (K_ATP) agonist. SR 47063 selectively activates K_ATP channels in vascular smooth muscle cells (IC₅₀: 8.1 nM in human saphenous vein, 3.86 nM in rat aorta). SR 47063 promotes potassium efflux and cellular hyperpolarization to induce vasorelaxation. SR 4706 is promising for research of hypertension and related cardiovascular disorders.

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CAS No.: 135809-60-8
화학식: C₁₇H₁₄N₄O₃
분자량:322.32

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

SR 47063 Chemical Structure

CAS No.: 135809-60-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

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Chemical Information

CAS No. 135809-60-8
분자량 322.32
화학식 C₁₇H₁₄N₄O₃
SMILES

N#C/N=C1C=CC=CN\1C2=CC(C)(C)OC3=C2C=C([N+]([O-])=O)C=C3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Criddle DN, et al. Vasorelaxant effects of the potassium channel opener SR 47063 on the isolated human saphenous vein and rat aorta. Braz J Med Biol Res. 2000 Aug;33(8):961-6. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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