Tabernanthine
Tabernanthine is a negative chronotropic and negative inotropic agent that selectively acts on sinoatrial node receptors, regulating heart rhythm and myocardial contractility. Tabernanthine exhibits atropine resistance and direct non-cholinergic binding properties, acting directly on the sinoatrial node rather than relying on vagal nerve or cholinergic pathways to exert its key activity of slowing heart rate and weakening myocardial contractility. Tabernanthine is useful in cardiovascular pharmacology research, particularly in the areas of sinoatrial node function regulation, mechanisms related to bradycardia, and studies of cardiac receptor subtype differences.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 83-94-3
- 화학식: C20H26N2O
- 분자량:310.43
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 83-94-3
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분자량 310.43
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화학식 C20H26N2O
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SMILES
CC[C@@H]1[C@@]2([H])[C@]3([H])C4=C(CC[N@]2C[C@@](C1)([H])C3)C5=CC=C(OC)C=C5N4
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Zetler G, et al. Die Wirkung von 11 Indol-Alkaloiden auf das Meerschweinchen-Herz in vivo und in vitro, verglichen mit 2 synthetischen Azepinoindolen, Chinidin und Quindonium [Action of 11 indole alkaloids on the guinea pig heart in vivo and in vitro, compared with those of 2 synthetic azepinoindoles, quinidine and quindonium]. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1968 May 7;260(1):26-49. German. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)