Viomellein
Viomellein is a SUMOylation inhibitor with antibacterial and anticancer activities. Viomellein inhibits biofilm formation of strains produced from the fungus Aspergillus ochraceus from the Mediterranean sponge Agelas oroides. Viomellein exhibits cytotoxicity against A2780 human ovarian cancer cells with an IC50 value of 5.0 μM. Viomellein also inhibits SUMOylation of RanGAP1 (GTPase activating protein) with an IC50 of 10.2 μM.
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- CAS No.: 55625-78-0
- 화학식: C30H24O11
- 분자량:560.50
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
Chemical Information
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CAS No. 55625-78-0
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분자량 560.50
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화학식 C30H24O11
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SMILES
O=C1C2=C(O)C3=C(C(C(OC)=C(C4=C(OC)C=C5C=C(C[C@@H](C)O6)C(C6=O)=C(O)C5=C4O)C3=O)=O)C=C2C[C@@H](C)O1
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Structure Classification
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Initial Source
Aspergillus ochraceus
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Kumla D, et al. 1,3-Dioxepine and spiropyran derivatives of viomellein and other dimeric naphthopyranones from cultures of Aspergillus elegans KUFA0015 and their antibacterial activity. Phytochemistry. 2021 Jan;181:112575 [Content Brief]
[2]. Hirohama M, et al. Spectomycin B1 as a novel SUMOylation inhibitor that directly binds to SUMO E2. ACS Chem Biol. 2013 Dec 20;8(12):2635-42. [Content Brief]
[3]. Cryptic Secondary Metabolites from the Sponge-Associated Fungus Aspergillus ochraceus
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Viomellein Related Classifications
HY-123888 Related Classifications
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