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Cat. No.: HY-149593

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VU0506013

Name: VU0506013
Brand: MedChemExpress
SKU: HY-149593
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VU0506013 is a selective positive allosteric modulator of Y4R (K_B = 34.9 nM). VU0506013 can be used in the development of anti-obesity agents targeting Y4R.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1207036-87-0

화학식: C₂₀H₂₃N₃O₄

분자량:369.41

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

VU0506013 Chemical Structure

CAS No.: 1207036-87-0

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Data Download

Data Sheet (267 KB)

Handling Instructions (2659 KB)

To place orders, for customer services and technical support, please contact:

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주변의 대리점 찾기 Your local distributor: Hycultec GmbHHycultec

Biological Activity

Chemical Information

Protocol

순도&문서

References

Help & FAQs

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

All Neuropeptide Y Receptor Isoforms
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NPY Y₁ receptor

NPY Y₂ receptor

NPY Y₄ receptor

NPY Y₅ receptor

Biological Activity

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IC₅₀ & Target

Chemical Information

순도&문서

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Calculators

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Classifications

Bioz

Biological Activity

제품 설명

VU0506013 is a selective positive allosteric modulator of Y4R (K_B = 34.9 nM). VU0506013 can be used in the development of anti-obesity agents targeting Y4R^[1].

IC₅₀ & Target
^[1]

NPY Y₄ receptor

All Neuropeptide Y Receptor Isoforms :

NPY Y₁ receptor

NPY Y₂ receptor

NPY Y₄ receptor

NPY Y₅ receptor

Chemical Information

CAS No. 1207036-87-0

분자량 369.41

화학식 C₂₀H₂₃N₃O₄

SMILES

O=C(N1CCCC1)C(C=C2NC(COC3=C(C)C=CC=C3)=O)=CN(C)C2=O

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)

COA (2659 KB)

Elemental Analysis Report (2659 KB)

HNMR (2659 KB)

CNMR (2659 KB)

RP-HPLC (2659 KB)

NP-HPLC (2659 KB)

MS (2659 KB)

LCMS (2659 KB)

IR (2659 KB)

GC (2659 KB)

OR (2659 KB)

SDS-PAGE (2659 KB)

SEC-HPLC (2659 KB)

Other Report (2659 KB)

Handling Instructions (2659 KB)

References

[1]. Schüß C, et al. Structure-Activity Relationship Study of the High-Affinity Neuropeptide Y4 Receptor Positive Allosteric Modulator VU0506013. J Med Chem. 2023 Jul 13;66(13):8745-8766. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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Concentration Concentration

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Volume Volume

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Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

×

Volume _(start) Volume _(start)

=

Concentration _(final) Concentration _(final)

×

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

VU0506013 Related Classifications

HY-149593 Related Classifications

GPCR/G Protein Neuronal Signaling

Neuropeptide Y Receptor

Disease Areas

Metabolic or Endocrine Disease

Metabolic Disease

Bioz

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Keywords

VU0506013
1207036-87-0
VU 0506013
VU-0506013
Neuropeptide Y Receptor
obesity
Inhibitor
inhibitor
inhibit

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VU0506013

All Neuropeptide Y Receptor Isoforms

Biological Activity

제품 설명

IC50 & Target

Chemical Information

순도&문서

References

Calculators

Help & FAQs

VU0506013 Related Classifications

HY-149593 Related Classifications

Bioz

Keywords

Your Recently Viewed Products

IC₅₀ & Target