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Cat. No.: HY-160530

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WEE1-IN-6

WEE1-IN-6 (compound 110) is a orally active WEE1 inhibitor with an DC₅₀ value of ≦ 100 nM. WEE1-IN-6 inhibits cell proliferation.

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CAS No.: 2928524-08-5
화학식: C₄₅H₅₂FN₁₁O₄
분자량:829.96

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

WEE1-IN-6 Chemical Structure

CAS No.: 2928524-08-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

WEE1-IN-6 (compound 110) is a orally active WEE1 inhibitor with an DC₅₀ value of ≦ 100 nM. WEE1-IN-6 inhibits cell proliferation^[1].

IC₅₀ & Target

DC₅₀: ≦ 100 nM (WEE1)^[1]

All Wee1 Isoforms :

PKMYT1

In Vitro

WEE1-IN-6 (compound 110) shows anti-proliferation activity with an IC₅₀ value of ≦ 25 nM in H1048 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2928524-08-5
분자량 829.96
화학식 C₄₅H₅₂FN₁₁O₄
SMILES

FC1=C(C=CC(NC2C(NC(CC2)=O)=O)=C1)N(CC3)CCC3CN(CC4)CCN4C(C=C5)=CC=C5NC6=NC7=C(C(N(CC=C)N7C8=NC([C@@](O)(CC)CC9)=C9C=C8)=O)C=N6
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Fu Liqiang, et al. Wee1 protein kinase degradation agent and use thereof. WO2023083194A1.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
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WEE1-IN-6

All Wee1 Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

WEE1-IN-6 Related Classifications

HY-160530 Related Classifications