WIC1
Based on 1 Customer Validation
WIC1 is a potent Wnt inhibitor. WIC1 can be used for the research of cancer.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.94%
- CAS No.: 943083-58-7
- 화학식: C22H23N3O3
- 분자량:377.44
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Cancer Stem Cells Compound Library
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Extracellular Vesicles (EVs) Compound Library
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Bioactive Compound Library Max
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MCE Bioactive Compound Library
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Bioactive Compound Library
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Anti-Fibrosis Compound Library
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High-Throughput Bioactive Compound Library
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Anti-Rheumatic Arthritis Compound Library
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Stem Cell Signaling Compound Library
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Wnt/Hedgehog/Notch Compound Library
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Anti-Cancer Compound Library
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Anti-Aging Compound Library
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Biological Activity
WICl (10 nM, 100 nM, 10μM, 100 μM) decrease TFC/LEF luciferase reporter activity in BEAS2B cell[1].
WICl (10 nM, 100 nM, 10μM, 100 μM) shows minimal toxicity.
WICl (1μM) displays a significant reduction in ABSC proliferation[1].
WICl decreases mRNA expression of 145 known downstream Wnt signaling target genes such as CCND1, MYC, and CTNNB1[1].
WICl (1μM) decreases the nuclear localization[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 943083-58-7
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Appearance Solid
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분자량 377.44
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화학식 C22H23N3O3
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Color Yellow to orange
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SMILES
O=C(C1=CC2=CC=CC=C2OC1=O)NC3=CC=C(N4CCN(CC)CC4)C=C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 1.67 mg/mL (4.42 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6494 mL | 13.2471 mL | 26.4943 mL | 66.2357 mL |
WIC1 Related Classifications
HY-153580 Related Classifications
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