KVS0001 (Standard)
KVS0001 (Standard) is the analytical standard of KVS0001 (HY-161111). This product is intended for research and analytical applications. KVS0001 is a selective SMG1 inhibitor. KVS0001 elevates the expression of transcripts and proteins resulting from truncating mutations. KVS0001 increased the presentation of immune-targetable HLA class I-associated peptides from nonsense-mediated decay (NMD)-downregulated proteins on the surface of cancer cells. KVS0001 exerts anti-tumor properties and can be studied in research for NMD-related diseases, including cancer and inherited diseases.
For research use only. We do not sell to patients.
- CAS No.: 3056394-59-0
- Formula: C27H27ClN8O3S
- Molecular Weight:579.07
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 3056394-59-0
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Molecular Weight 579.07
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Formula C27H27ClN8O3S
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SMILES
ClC1=C(S(N2CCNCC2)(=O)=O)C=C(NC3=NC=CC(C4=CC(C5=CC=C(NC(NC)=O)C=C5)=NC=C4)=N3)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)