KVS0001 (Standard)

KVS0001 (Standard) is the analytical standard of KVS0001 (HY-161111). This product is intended for research and analytical applications. KVS0001 is a selective SMG1 inhibitor. KVS0001 elevates the expression of transcripts and proteins resulting from truncating mutations. KVS0001 increased the presentation of immune-targetable HLA class I-associated peptides from nonsense-mediated decay (NMD)-downregulated proteins on the surface of cancer cells. KVS0001 exerts anti-tumor properties and can be studied in research for NMD-related diseases, including cancer and inherited diseases.

For research use only. We do not sell to patients.

  • CAS No.: 3056394-59-0
  • Formula: C27H27ClN8O3S
  • Molecular Weight:579.07
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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