1. Metabolic Enzyme/Protease
  2. Phosphatase
  3. L-690330

L-690330 

Cat. No.: HY-101075 Purity: >98.0%
Handling Instructions

L-690330 is a competitive inhibitor of inositol monophosphatase (IMPase) with Kis of 0.27 and 0.19 μM for recombinant human and bovine IMPase, 0.30 and 0.42 μM for human and bovine frontal cortex IMPase, respectively. L-690330 exhibits 10-fold more sensitive than mouse and rat IMPase.

For research use only. We do not sell to patients.

L-690330 Chemical Structure

L-690330 Chemical Structure

CAS No. : 142523-38-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 176 In-stock
Estimated Time of Arrival: December 31
5 mg USD 160 In-stock
Estimated Time of Arrival: December 31
10 mg USD 260 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

L-690330 is a competitive inhibitor of inositol monophosphatase (IMPase) with Kis of 0.27 and 0.19 μM for recombinant human and bovine IMPase, 0.30 and 0.42 μM for human and bovine frontal cortex IMPase, respectively. L-690330 exhibits 10-fold more sensitive than mouse and rat IMPase[1].

IC50 & Target

Ki: 0.27 μM (Recombinant human IMPase), 0.19 μM (Recombinant bovine IMPase), 0.30 μM (Human frontal cortex IMPase), 0.42 μM (Bovine frontal cortex IMPase)[1]

Molecular Weight

298.12

Formula

C₈H₁₂O₈P₂

CAS No.

142523-38-4

SMILES

OC1=CC=C(OC(P(O)(O)=O)(P(O)(O)=O)C)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 33.33 mg/mL (111.80 mM; Need ultrasonic)

DMSO : 25 mg/mL (83.86 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3544 mL 16.7718 mL 33.5435 mL
5 mM 0.6709 mL 3.3544 mL 6.7087 mL
10 mM 0.3354 mL 1.6772 mL 3.3544 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (8.39 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (8.39 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (8.39 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: >98.0%

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Keywords:

L-690330L690330L 690330PhosphataseInhibitorinhibitorinhibit

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Product name:
L-690330
Cat. No.:
HY-101075
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