LasR-IN-4
Based on 1 Customer Validation
LasR-IN-4 is a potent LasR inhibitor. LasR-IN-4 can inhibit Pseudomonas aeruginosa and its biofilm formation, pyocyanin production, and rhamnolipids production.
For research use only. We do not sell to patients.
- Purity: 99.52%
- CAS No.: 183488-96-2
- Formula: C18H20N4
- Molecular Weight:292.38
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MIC: 56.25 μg/mL (P. aeruginosa)[1]
LasR-IN-4 (compound 3d) has inhibitory activity against P. aeruginosa with MIC of 56.25 μg/mL, and inhibits biofilm formation, pyocyanin production, and rhamnolipids production of 71.70%, 68.70% and 54.00%, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 183488-96-2
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Appearance Solid
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Molecular Weight 292.38
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Formula C18H20N4
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Color Off-white to light yellow
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SMILES
CN1CCN(C2=CC=C(C3=NC4=CC=CC=C4N3)C=C2)CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (171.01 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4202 mL | 17.1010 mL | 34.2021 mL | 85.5052 mL |
| 5 mM | 0.6840 mL | 3.4202 mL | 6.8404 mL | 17.1010 mL | |
| 10 mM | 0.3420 mL | 1.7101 mL | 3.4202 mL | 8.5505 mL | |
| 15 mM | 0.2280 mL | 1.1401 mL | 2.2801 mL | 5.7003 mL | |
| 20 mM | 0.1710 mL | 0.8551 mL | 1.7101 mL | 4.2753 mL | |
| 25 mM | 0.1368 mL | 0.6840 mL | 1.3681 mL | 3.4202 mL | |
| 30 mM | 0.1140 mL | 0.5700 mL | 1.1401 mL | 2.8502 mL | |
| 40 mM | 0.0855 mL | 0.4275 mL | 0.8551 mL | 2.1376 mL | |
| 50 mM | 0.0684 mL | 0.3420 mL | 0.6840 mL | 1.7101 mL | |
| 60 mM | 0.0570 mL | 0.2850 mL | 0.5700 mL | 1.4251 mL | |
| 80 mM | 0.0428 mL | 0.2138 mL | 0.4275 mL | 1.0688 mL | |
| 100 mM | 0.0342 mL | 0.1710 mL | 0.3420 mL | 0.8551 mL |
LasR-IN-4 Related Classifications
HY-151167 Related Classifications
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