LDHA-IN-6
LDHA-IN-6 (compound 6) is an oral bioactive inhibitor of lactate dehydrogenase-A (LDHA), with the IC50 of 46 nM. LDHA-IN-6 has antitumor activity.
For research use only. We do not sell to patients.
- CAS No.: 3043790-18-4
- Formula: C23H20F3N3O4
- Molecular Weight:459.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MIA PaCa-2 | IC50 |
25.552 μM
Compound: 6
|
Antiproliferative activity against human MIA PaCa-2 cells incubated for 48 hrs by Hoechst 33342 and SYTOX green staining based confocal imaging analysis
Antiproliferative activity against human MIA PaCa-2 cells incubated for 48 hrs by Hoechst 33342 and SYTOX green staining based confocal imaging analysis
|
[PMID: 38925013] |
| PANC-1 | IC50 |
23.944 μM
Compound: 6
|
Antiproliferative activity against human PANC-1 cells incubated for 48 hrs by Hoechst 33342 and SYTOX green staining based confocal imaging analysis
Antiproliferative activity against human PANC-1 cells incubated for 48 hrs by Hoechst 33342 and SYTOX green staining based confocal imaging analysis
|
[PMID: 38925013] |
Chemical Information
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CAS No. 3043790-18-4
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Molecular Weight 459.42
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Formula C23H20F3N3O4
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SMILES
O=C(OC)C(C1=CC=C(C(F)(F)F)C=C1)CC(NC2=CC=C(C(C3=NC=CN3C)=O)C=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)