Lepidiline B
Lepidiline B is a flavonolignan isolated from the roots of Brassicaceae Lepidium meyenii. Lepidiline B exhibits anti-inflammation activities in human cancer cell lines.
For research use only. We do not sell to patients.
- CAS No.: 596093-97-9
- Formula: C20H23ClN2
- Molecular Weight:326.86
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | ED50 |
>10 μg/mL
Compound: 2, lepidiline B
|
Cytotoxicity against human A549 cells
Cytotoxicity against human A549 cells
|
[PMID: 12932133] |
| HL-60 | IC50 |
3.8 μM
Compound: 1b
|
Cytotoxicity against human HL-60 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Cytotoxicity against human HL-60 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 34808062] |
| HT-29 | ED50 |
>10 μg/mL
Compound: 2, lepidiline B
|
Cytotoxicity against human HT-29 cells
Cytotoxicity against human HT-29 cells
|
[PMID: 12932133] |
| HUVEC | IC50 |
>100 μM
Compound: 1b
|
Cytotoxicity against HUVEC cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Cytotoxicity against HUVEC cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 34808062] |
| MCF7 | IC50 |
>100 μM
Compound: 1b
|
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
|
[PMID: 34808062] |
| MDA-MB-231 | ED50 |
1.66 μg/mL
Compound: 2, lepidiline B
|
Cytotoxicity against human MDA231 cells
Cytotoxicity against human MDA231 cells
|
[PMID: 12932133] |
| MIA PaCa-2 | ED50 |
1.38 μg/mL
Compound: 2, lepidiline B
|
Cytotoxicity against human MIAPaCa2 cells
Cytotoxicity against human MIAPaCa2 cells
|
[PMID: 12932133] |
| PC-3 | ED50 |
>10 μg/mL
Compound: 2, lepidiline B
|
Cytotoxicity against human PC3 cells
Cytotoxicity against human PC3 cells
|
[PMID: 12932133] |
| UMUC3 | ED50 |
6.47 μg/mL
Compound: 2, lepidiline B
|
Cytotoxicity against human UM-UC-3 cells
Cytotoxicity against human UM-UC-3 cells
|
[PMID: 12932133] |
Chemical Information
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CAS No. 596093-97-9
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Molecular Weight 326.86
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Formula C20H23ClN2
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SMILES
CC1=C(C)[N+](CC2=CC=CC=C2)=C(C)N1CC3=CC=CC=C3.[Cl-]
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Baoliang Cui, et al. Imidazole alkaloids from Lepidium meyenii. J Nat Prod. 2003 Aug;66(8):1101-3. [Content Brief]
[2]. Naisheng Bai, et al. Flavonolignans and other constituents from Lepidium meyenii with activities in anti-inflammation and human cancer cell lines. J Agric Food Chem. 2015 Mar 11;63(9):2458-63. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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