Bile Acids

(25R)-3α,7α,12α-Trihydroxy-5β-cholestan-26-oyl-CoA is a nucleoside metabolite.

N-Cholyl-L-leucine is a bile acid-amino acid conjugate, mainly produced by intestinal microorganisms. N-Cholyl-L-leucine can be used as a biomarker for premature infants and is also employed in the study of bile acid metabolism.

Homocholic acid is a synthetic steroid analogue. Homocholic acid can be labeled with 75Se and is used for SeHCAT detection (a method for diagnosing bile acid malabsorption).

N-Choloylphenylalanine (Compound 6273) (PheCA) is a VPR-induced growth arrest inhibitor. N-Choloylphenylalanine alleviates VPR-induced growth arrest. N-Choloylphenylalanine can be used in yeast and HIV-1 infection research.

Tauroursocholic acid (TUCA) sodium is a taurine-conjugated form of the bile acid ursocholic acid and the 7β-hydroxy epimer of Taurocholic acid (HY-B1788). Tauroursocholic acid sodium exists in abundance during the biliary tract cancer, disrupting the balance and cellular toxicity of bile acids and inducing carcinogenesis through oxidative DNA damage and DNA mutation. Tauroursocholic acid (TUCA) sodium can be used for biliary tract cancer research.

3β,4β,7α,12α-THBA is a cholic acid.

3α,6α,7α,12α-Tetrahydroxy bile acid is a hydrophilic tetrahydroxy derivative of bile acids.

3α,12α-Dihydroxy-5β-cholestanoic acid is a cholestenoic acid.

Deoxycholoyl-CoA (Deoxycholoyl-coenzyme A) is a coenzyme A derivative.

5β-Cholestane-3α,7α,12α,25-tetrol (3α,7α,12α,25-Tetrahydroxycoprostane) is a bile acid alcohol. 5β-Cholestane-3α,7α,12α,25-tetrol is a GPBAR1 (also known as TGR5) activator (EC₅₀: 1.36 μM). 5β-Cholestane-3α,7α,12α,25-tetrol is the predominant bile-alcohol disease marker present in patients with Cerebrotendinous xanthomatosis (CTX).

3-Oxo-delta4-chenodeoxycholyl-CoA (3-Oxo-delta4-chenodeoxycholyl-coenzyme A) is a derivative of coenzyme A.

(24R,25R)-3Alpha,7alpha,12alpha,24-Tetrahydroxy-5beta-cholestan-26-oyl-CoA ((24R,25R)-3Alpha,7alpha,12alpha,24-Tetrahydroxy-5beta-cholestanoyl-coenzyme A) is an acyl-CoA.

(25S)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoyl-CoA ((25S)-THCA-Coenzyme A) is a 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA.

3β,7β-Dihydroxy-5-cholestenoic acid is a C27 acid that displays elevated levels in Niemann-Pick type C and Niemann-Pick type B diseases, contributing to toxicity in oculomotor neurons. It is synthesized from 3β-hydroxy-7-oxocholest-5-en-(25R)26-oic acid (3βH,7O-CA) through the enzymatic action of hydroxysteroid 11-β dehydrogenase 1.

5-Cholestene-26-oic acid-3β-ol is a cholesterol catabolite.

Deoxycholic acid (cholanoic acid) sodium hydrate, a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptorTGR5.

Cholic acid sodium hydrate is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. Cholic acid sodium hydrate facilitates fat absorption and cholesterol excretion. Cholic acid sodium hydrate is orally active.

Deoxycholic acid 3-sulfate disodium is a steroid bile salt, a sulfate derivative of the bile acid (BA) deoxycholic acid.

Tauroisolithocholanoic acid sodium is an isomer of the naturally occurring Taurolithocholic acid (HY-113308).

Glyco-ω-muricholanoic acid is an endogenous metabolite and a glycine conjugated bile acid (BA) of ω-Muricholanoic Acid.