Lipid Classification

Lipoxin A5 is an eicosapentaenoic acid derived from pig white blood cells. Lipoxin A5 slowly contracted the guinea pig lung parenchymal strips with a contractile force similar to that of LXA4 and LXB4.2, but LXA5 did not have the vasodilating effect on the aortic smooth muscle shown by LXA4 and LXB4.2.

(14Z)-14-Eicosenoic acid is an unsaturated fatty acid isolated from sponges.

Stearoyl-L-carnitine-d9 chloride is the deuterium labeled Stearoyl-L-carnitine chloride. Stearoyl-L-carnitine chloride, a fatty ester lipid molecule, is an endogenous metabolite. Stearoyl-L-carnitine chloride can be used as PKC inhibitor. Stearoyl-L-carnitine chloride accumulates in β cells, leading to arrest of insulin synthesis and energy deficiency in type 2 diabetes mouse. Stearoyl-L-carnitine chloride inhibits lecithin cholesterol acyltransferase (LCAT) in rat and rabbits plasma. Stearoyl-L-carnitine chloride acts as a metabolomics biomarker for Parkinson’s disease. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2.

3-Hydroxybutyryl-CoA is a metabolite which can be found in mouse or E.coli, et al. 3-Hydroxybutyryl-CoA has a 3-hydroxybutanoyl as the S-acyl component, and is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan.

9(Z),11(Z)-octadecadienoic acid is an isomer of linoleic acid and has antitumor activity (EC ₅₀ = 446.1 µM).

Tigloyl-CoA (Tiglyl-coenzyme A) is an intermediate product of isoleucine metabolism. Tigloyl-CoA is an inhibitor of N-acetylglutamate synthetase.

Quercetin 3-O-β-D-glucuronide-6″-methyl ester is a flavonoid isolated from Atraphaxis spinosa L.

6-Hydroxykaempferol 3-O-β-rutinoside-6-O-β-D-glucoside is a potent antioxidant that can be isolated from Carthamus tinctorius.

1α,25-Dihydroxyprevitamin D3 is the precursor of Vitamin D3.

(E)-3-Methyl-2-hexenoic acid-d5 ((2E)-3-Methyl-2-hexenoic acid-d5) is a deuterium labeled (E)-3-Methyl-2-hexenoic acid. (E)-3-Methyl-2-hexenoic acid is an axillary odor-related compound.

(-)-Epicatechin 3-(3-O-methylgallate) is a catechin, that can be isolated from tea leaf. (-)-Epicatechin 3-(3-O-methylgallate) shows anti-inflammatory activity.

Mearnsetin is a compound that can be isolated from Elaeocarpus lanceofolius. Mearnsetin has antioxidative properties.

Araneosol (Compound 2) is a flavonoid that can be isolated from Herissantia tiubae.

(-)-Latifolin, a flavonoid, induces apoptotic cell death by targeting PI3K/AKT/mTOR/p70S6K signaling. (-)-Latifolin significantly inhibits the cell proliferation of oral squamous cell carcinoma (OSCC), and causes the anti-metastatic activities by effectively blocking cell migration, invasion, and adhesion via the inactivation of FAK/Src. (-)-Latifolin suppresses autophagic-related proteins and autophagosome formation. (-)-Latifolin inhibits necroptosis by dephosphorylating necroptosis-regulatory proteins (RIP1, RIP3, and MLKL). (-)-Latifolin has beneficial effects on anti-aging, anti-carcinogenic, anti-inflammatory, and cardio-protective activities.

Peltatoside is a flavone which can be extracted from Annona crassilfora Mart, with an anti-inflammatory activity and can be used for relative research.

5-Hydroxydecanoic acid (5-HD） is a K_ATP channel antagonist，which has the effect of blocking the K K_ATP channel only during ischaemia by competing with the ATP binding site and does not affect pancreatic K_ATP channels.

Glycyrrhiza-flavonol A (compound 4) is a natural product of Glycyrrhiza, Fabaceae.

Geranylacetone is a natural compound isolated from the stems of Ferula akitschkensis.

2',6'-Dihydroxy-4'-methoxydihydrochalcone is an orally active dihydrochalcone compound with antiplasmodial and anti-inflammatory activities. 2',6'-Dihydroxy-4'-methoxydihydrochalcone reduces the IL-1β, TNF, and nitrite levels in vitro.

Hesperetin 5-β-D-glucopyranoside is a flavonoid component, that can be isolated from Prunus davidiana.