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Cat. No.: HY-162015

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LTA4H-IN-2

LTA4H-IN-2 (compound (S)-2 ) is an orally active inhibitor of Leukotriene A4 Hydrolase, with an IC₅₀ of <3 nM.

For research use only. We do not sell to patients.

CAS No.: 2851480-52-7
Formula: C₂₀H₁₉FN₆O₂
Molecular Weight:394.40

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

LTA4H-IN-2 Chemical Structure

CAS No.: 2851480-52-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

LTA4H-IN-2 (compound (S)-2 ) is an orally active inhibitor of Leukotriene A4 Hydrolase, with an IC₅₀ of <3 nM^[1].

IC₅₀ & Target

IC50: <3 nM (Leukotriene A4 Hydrolase)^[1].

All Aminopeptidase Isoforms :

CD13
LTA4H

Chemical Information

CAS No. 2851480-52-7
Molecular Weight 394.40
Formula C₂₀H₁₉FN₆O₂
SMILES

N[C@@H](CN1C=CC(C2=CC=C(OC3=NC=C(C4=CC=NN4)C=C3F)C=C2)=N1)CO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gebhard Thoma, et al. Discovery of Amino Alcohols as Highly Potent, Selective, and Orally Efficacious Inhibitors of Leukotriene A4 Hydrolase. J Med Chem. 2023 Dec 14;66(23):16410-16425. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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LTA4H-IN-2

All Aminopeptidase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

LTA4H-IN-2 Related Classifications

HY-162015 Related Classifications