lunresertib (Standard)
lunresertib (Standard) is the analytical standard of lunresertib (HY-145817A). This product is intended for research and analytical applications. lunresertib (RP-6306) is a potent, selective and orally active PKMYT1 inhibitor with an IC50 of 14 nM. lunresertib shows a high degree of selectivity over other Kinases in cellular binding assays. lunresertib shows anticancer effects.
For research use only. We do not sell to patients.
- CAS No.: 2719793-90-3
- Formula: C18H20N4O2
- Molecular Weight:324.38
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Purity & Documentation
-
Help & FAQs
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 2719793-90-3
-
Molecular Weight 324.38
-
Formula C18H20N4O2
-
SMILES
O=C(C1=C(N)[N@]([C@]2=C(C)C(O)=CC=C2C)C3=NC(C)=C(C)C=C31)N
-
Synonyms
RP-6306 (Standard)
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Janek Szychowski, et al. Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306. J Med Chem. 2022 Aug 11;65(15):10251-10284. [Content Brief]
[2]. David Gallo, et al. CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition. Nature. 2022 Apr;604(7907):749-756. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
lunresertib (Standard) Related Classifications
HY-145817AR Related Classifications
Powered by Bioz