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LY88074 

Cat. No.: HY-135585
Handling Instructions

LY88074 (Compound 88074) is a Raloxifene analog lacking the basic side chain. Raloxifene is a selective estrogen receptor modulator, and reduces fracture risk at least in part by improving the mechanical properties of bone in a cell- and estrogen receptor-independent manner.

For research use only. We do not sell to patients.

LY88074 Chemical Structure

LY88074 Chemical Structure

CAS No. : 177744-96-6

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Description

LY88074 (Compound 88074) is a Raloxifene analog lacking the basic side chain. Raloxifene is a selective estrogen receptor modulator, and reduces fracture risk at least in part by improving the mechanical properties of bone in a cell- and estrogen receptor-independent manner[1].

In Vitro

Removal of the aminoethylpiperdine moiety, as in LY88074 (Compound 88074), reduces bone binding, compared to Raloxifene. The interaction of LY88074 with collagen matrix, although significant, is less than the interaction found with Raloxifene[1].

Molecular Weight

362.40

Formula

C₂₁H₁₄O₄S

CAS No.

177744-96-6

SMILES

O=C(C1=C(C2=CC=C(O)C=C2)SC3=CC(O)=CC=C31)C4=CC=C(O)C=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

LY88074LY 88074LY-88074OthersRaloxifenebonebindingcollagenmatrixInhibitorinhibitorinhibit

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LY88074
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