2. Metabolic Enzyme/Protease
  3. Mitochondrial Metabolism
  4. M7594_0037

M7594_0037 is a potent inhibitor of human peptide deformylase (HsPDF) that has anti-tumor activity.

For research use only. We do not sell to patients.

M7594_0037

M7594_0037 Chemical Structure

CAS No. : 774551-07-4

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Description

M7594_0037 is a potent inhibitor of human peptide deformylase (HsPDF) that has anti-tumor activity[1].

Molecular Weight

387.86

Formula

C20H22ClN3O3
CAS No.
Appearance

Solid

Color

Off-white to yellow

SMILES

O=C(COC1=C(C=C(C=C1Cl)CNCCC2=CNC3=C2C=CC=C3)OC)N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (128.91 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5782 mL 12.8912 mL 25.7825 mL
5 mM 0.5156 mL 2.5782 mL 5.1565 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.58%

SDS (252 KB)

COA (253 KB) HNMR (188 KB) LCMS (153 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5782 mL 12.8912 mL 25.7825 mL 64.4562 mL
5 mM 0.5156 mL 2.5782 mL 5.1565 mL 12.8912 mL
10 mM 0.2578 mL 1.2891 mL 2.5782 mL 6.4456 mL
15 mM 0.1719 mL 0.8594 mL 1.7188 mL 4.2971 mL
20 mM 0.1289 mL 0.6446 mL 1.2891 mL 3.2228 mL
25 mM 0.1031 mL 0.5156 mL 1.0313 mL 2.5782 mL
30 mM 0.0859 mL 0.4297 mL 0.8594 mL 2.1485 mL
40 mM 0.0645 mL 0.3223 mL 0.6446 mL 1.6114 mL
50 mM 0.0516 mL 0.2578 mL 0.5156 mL 1.2891 mL
60 mM 0.0430 mL 0.2149 mL 0.4297 mL 1.0743 mL
80 mM 0.0322 mL 0.1611 mL 0.3223 mL 0.8057 mL
100 mM 0.0258 mL 0.1289 mL 0.2578 mL 0.6446 mL
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M7594_0037 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

M7594_0037774551-07-4Mitochondrial Metabolismhigh-throughput virtual screeninganticancerInhibitorinhibitorinhibit

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