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  5. Macrozamin

Macrozamin is a major constituent principle of Cycads. Macrozamin has carcinogenic, mutagenic, teratogenic and neurotoxic properties.

For research use only. We do not sell to patients.

Macrozamin Chemical Structure

Macrozamin Chemical Structure

CAS No. : 6327-93-1

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Based on 1 publication(s) in Google Scholar

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Description

Macrozamin is a major constituent principle of Cycads. Macrozamin has carcinogenic, mutagenic, teratogenic and neurotoxic properties[1].

Molecular Weight

384.34

Formula

C13H24N2O11

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]([C@H]([C@@H]([C@@H](CO[C@H]1[C@@H]([C@H]([C@@H](CO1)O)O)O)O2)O)O)[C@@H]2OC/N=[N+](C)\[O-]

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (260.19 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6019 mL 13.0093 mL 26.0186 mL
5 mM 0.5204 mL 2.6019 mL 5.2037 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.6019 mL 13.0093 mL 26.0186 mL 65.0466 mL
5 mM 0.5204 mL 2.6019 mL 5.2037 mL 13.0093 mL
10 mM 0.2602 mL 1.3009 mL 2.6019 mL 6.5047 mL
15 mM 0.1735 mL 0.8673 mL 1.7346 mL 4.3364 mL
20 mM 0.1301 mL 0.6505 mL 1.3009 mL 3.2523 mL
25 mM 0.1041 mL 0.5204 mL 1.0407 mL 2.6019 mL
30 mM 0.0867 mL 0.4336 mL 0.8673 mL 2.1682 mL
40 mM 0.0650 mL 0.3252 mL 0.6505 mL 1.6262 mL
50 mM 0.0520 mL 0.2602 mL 0.5204 mL 1.3009 mL
60 mM 0.0434 mL 0.2168 mL 0.4336 mL 1.0841 mL
80 mM 0.0325 mL 0.1626 mL 0.3252 mL 0.8131 mL
100 mM 0.0260 mL 0.1301 mL 0.2602 mL 0.6505 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Macrozamin
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