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United States

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Cat. No.: HY-N3323

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Mannioside A

Mannioside A is a steroidal saponin. Mannioside A is a nature product that could be isolated from Dracaena mannii. Mannioside A has anti-inflammatory effect.

For research use only. We do not sell to patients.

CAS No.: 1038922-95-0
Formula: C₃₉H₆₂O₁₃
Molecular Weight:738.90

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Mannioside A Chemical Structure

CAS No.: 1038922-95-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Mannioside A is a steroidal saponin. Mannioside A is a nature product that could be isolated from Dracaena mannii. Mannioside A has anti-inflammatory effect^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	42.95 μM Compound: manioside A	Cytotoxicity against human HCT116 cells by MTT assay Cytotoxicity against human HCT116 cells by MTT assay	[PMID: 20553003]
HT-29	IC₅₀	56.23 μM Compound: manioside A	Cytotoxicity against human HT-29 cells by MTT assay Cytotoxicity against human HT-29 cells by MTT assay	[PMID: 20553003]

In Vivo

Mannioside A (compound 1; 10 mg/kg; p.o.) inhibits carrageene-induced paw edema in rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Wistar rats^[1]
Dosage:

10 mg/kg
Administration:

oral administration
Result:

Had anti-inflammatory effects with maximum activity observed within 2 h.

Chemical Information

CAS No. 1038922-95-0
Molecular Weight 738.90
Formula C₃₉H₆₂O₁₃
SMILES

O[C@@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(C[C@H](CC5)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O[C@H]7[C@@H]([C@@H]([C@H]([C@@H](O7)C)O)O)O)O)=CC4)C)([H])CC3)([H])C[C@]1([H])O[C@]8(CC[C@H](CO8)C)[C@H]2C)C
Structure Classification
- Steroids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Tapondjou LA, et, al. In vivo anti-inflammatory effect of a new steroidal saponin, mannioside A, and its derivatives isolated from Dracaena mannii. Arch Pharm Res. 2008 May;31(5):653-8. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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