MAO-B-IN-37
MAO-B-IN-37 (Compound 37) is a derivative of TT01001 (HY-114520), and a selective inhibitor for monoamine oxidase B (MAO-B) with an IC50 of 270 nM. MAO-B-IN-37 exhibits good metabolic stability in mice microsomes and good affinity with human serum albumin.
For research use only. We do not sell to patients.
- CAS No.: 894280-02-5
- Formula: C14H12FN3O3
- Molecular Weight:289.26
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
|
MAO-B 0.27 μM (IC50) |
MAO-A 16 μM (IC50) |
Chemical Information
-
CAS No. 894280-02-5
-
Molecular Weight 289.26
-
Formula C14H12FN3O3
-
SMILES
O=C(NCC1=CC=C(F)C=C1)NC2=CC=C([N+]([O-])=O)C=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)