2. Peptides
  3. Semax

Semax is a nootropic neuroprotective peptide. Semax can be used in the research of brain stroke.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Semax Chemical Structure

Semax Chemical Structure

CAS No. : 80714-61-0

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other In-stock Forms of Semax:

Other Forms of Semax:

Semax Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Semax is a nootropic neuroprotective peptide. Semax can be used in the research of brain stroke[1][2].

In Vitro

Semax (25 μM and 100 μM, 48 h) reduces the Abeta oligomers (100 μM) levels[2].
Semax (100 nM) increase survival of cholinergic basal forebrain neurons[3].
Semax (100 nM) stimulates activity of choline acetyltransferase in dissociated basal forebrain tissue culture[3].
Semax (10 μM, 24 h) stimulates the synthesis of brain-derived neurotrophic factor (BDNF) in astrocytes cultured from rat basal forebrain[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Semax Related Antibodies
In Vivo

Semax (100 μg/kg, i.p.) promotes the formation and functioning of the vascular system in Ischemia (pMCAO) rats[1].
Semax (50 µg and 250 µg, 100 µL/kg, intranasal inhalation) increases levels of b BDNF protein in rat basal forebrain[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Ischemia (pMCAO) rats[1].
Dosage: 100 μg/kg
Administration: Intraperitoneal injections (i.p.), performed 15 min, 1, 4 and 8 h after permanent middle cerebral artery occlusion (pMCAO).
Result: Increased the immune response (upregulation of transcripts).
Animal Model: Rats[5]
Dosage: 50 µg, 250 µg, 100 µL/kg
Administration: Intranasal inhalation
Result: Increased levels of brain-derived neurotrophic factor (BDNF) protein in rat basal forebrain.
Molecular Weight

813.92

Formula

C37H51N9O10S
CAS No.
Sequence

Met-Glu-His-Phe-Pro-Gly-Pro
Sequence Shortening

MEHFPGP
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Semax80714-61-0OthersIschemiaBDNFastrocytesnootropicneuroprotectiveAbetaInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Semax
Cat. No.:
HY-P1146
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.