Methylamino-PEG2-Boc
Based on 1 Customer Validation
Methylamino-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.96%
- CAS No.: 1807521-04-5
- Formula: C12H25NO4
- Molecular Weight:247.33
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1807521-04-5
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Appearance Liquid (Density: 0.982±0.06 g/cm3)
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Molecular Weight 247.33
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Formula C12H25NO4
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Color Colorless to light yellow
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SMILES
O=C(OC(C)(C)C)CCOCCOCCNC
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Synonyms
Methylamino-PEG2-t-butyl ester
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 50 mg/mL (202.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.0432 mL | 20.2159 mL | 40.4318 mL | 101.0795 mL |
| 5 mM | 0.8086 mL | 4.0432 mL | 8.0864 mL | 20.2159 mL | |
| 10 mM | 0.4043 mL | 2.0216 mL | 4.0432 mL | 10.1080 mL | |
| 15 mM | 0.2695 mL | 1.3477 mL | 2.6955 mL | 6.7386 mL | |
| 20 mM | 0.2022 mL | 1.0108 mL | 2.0216 mL | 5.0540 mL | |
| 25 mM | 0.1617 mL | 0.8086 mL | 1.6173 mL | 4.0432 mL | |
| 30 mM | 0.1348 mL | 0.6739 mL | 1.3477 mL | 3.3693 mL | |
| 40 mM | 0.1011 mL | 0.5054 mL | 1.0108 mL | 2.5270 mL | |
| 50 mM | 0.0809 mL | 0.4043 mL | 0.8086 mL | 2.0216 mL | |
| 60 mM | 0.0674 mL | 0.3369 mL | 0.6739 mL | 1.6847 mL | |
| 80 mM | 0.0505 mL | 0.2527 mL | 0.5054 mL | 1.2635 mL | |
| 100 mM | 0.0404 mL | 0.2022 mL | 0.4043 mL | 1.0108 mL |
Methylamino-PEG2-Boc Related Classifications
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