Microgrewiapine A
Microgrewiapine A is an antagonist of nAChR. Microgrewiapine A inhibits hα4β2 and hα3β4 activity with 60% and 70% inhibition, respectively. Microgrewiapine A has selective cytotoxic against HT-29 human colon cancer cells with an IC50 of 6.8 μM.
For research use only. We do not sell to patients.
- CAS No.: 1420777-30-5
- Formula: C17H29NO
- Molecular Weight:263.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HT-29 | IC50 |
6.8 μM
Compound: 1, Microgrewiapine A
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Cytotoxicity against human HT-29 cells assessed as inhibition of cell proliferation after 3 days by SRB assay
Cytotoxicity against human HT-29 cells assessed as inhibition of cell proliferation after 3 days by SRB assay
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[PMID: 23327794] |
Chemical Information
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CAS No. 1420777-30-5
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Molecular Weight 263.42
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Formula C17H29NO
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SMILES
CCCC/C=C/C=C/C=C/[C@H]1N([C@H]([C@@H](CC1)O)C)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Microgrewiapine A Related Classifications
HY-N10132 Related Classifications
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