MK-4882
MK-4882 is an HCV NS5A inhibitor with activity in reducing viral load in a chimpanzee model of HCV infection, but with issues of viral breakthrough, prompting the development of compounds with greater potency against more genotypes and NS5A resistance mutations.
For research use only. We do not sell to patients.
- CAS No.: 1246470-32-5
- Formula: C42H50N8O7
- Molecular Weight:778.90
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
7 μM
Compound: MK-4882
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Cytotoxicity in human HuH7 replicon cells by MTS assay
Cytotoxicity in human HuH7 replicon cells by MTS assay
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[PMID: 29653894] |
Chemical Information
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CAS No. 1246470-32-5
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Molecular Weight 778.90
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Formula C42H50N8O7
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SMILES
O=C(N[C@@H](C(C)C)C(N1[C@@H](CCC1)C2=NC=C(N2)C3=CC=C(C=C3)C4=CC5=CC(C6=CN=C(N6)[C@H]7N(CCC7)C([C@H](C(C)C)NC(OC)=O)=O)=CC=C5O4)=O)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MK-4882 Related Classifications
HY-123649 Related Classifications
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