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Cat. No.: HY-122904

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ML377

ML377 is a selective triacylglyceride accumulation inhibitor with an IC₅₀ of 1.1 μM.

For research use only. We do not sell to patients.

CAS No.: 2650088-70-1
Formula: C₂₆H₂₄N₄O₃
Molecular Weight:440.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

ML377 Chemical Structure

CAS No.: 2650088-70-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

ML377 is a selective triacylglyceride accumulation inhibitor with an IC₅₀ of 1.1 μM^[1].

IC₅₀ & Target

IC₅₀: 1.1 μM (triacylglyceride accumulation)^[1]

All Endogenous Metabolite Isoforms :

Chemical Information

CAS No. 2650088-70-1
Molecular Weight 440.49
Formula C₂₆H₂₄N₄O₃
SMILES

O=C(C1=CC=CC(CN2CCOCC)=C1C2=O)NC3=CC=CC(C4=NC5=CC=CC=C5N4)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hershberger PM, et al. Inhibitors of Myocyte Triacylglyceride Accumulation. 2013 Dec 15 [updated 2015 Feb 11]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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ML377

All Endogenous Metabolite Isoforms