MO-I-500
MO-I-500 is a pharmacological of FTO inhibitor with an IC50 of 8.7 μM for the inhibition of purified FTO demethylase catalyzing demethylation of an artificial small methylated substrate. MO-I-500 can be used for the research of rare panresistant triple-negative inflammatory breast cancer.
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- Purity: 99.10%
- CAS No.: 1585219-04-0
- 화학식: C12H12ClNO5S
- 분자량:317.75
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
8.7 μM
Compound: 43; MO-I-500
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Antiproliferative activity human HeLa cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
Antiproliferative activity human HeLa cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
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[PMID: 38805939] |
Chemical Information
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CAS No. 1585219-04-0
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Appearance Solid
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분자량 317.75
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화학식 C12H12ClNO5S
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Color White to off-white
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SMILES
CCS(=O)(NC1=C(C(O)=C(O1)C2=CC=C(C=C2)Cl)O)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 31.8 mg/mL (100.08 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1471 mL | 15.7356 mL | 31.4713 mL | 78.6782 mL |
| 5 mM | 0.6294 mL | 3.1471 mL | 6.2943 mL | 15.7356 mL | |
| 10 mM | 0.3147 mL | 1.5736 mL | 3.1471 mL | 7.8678 mL | |
| 15 mM | 0.2098 mL | 1.0490 mL | 2.0981 mL | 5.2452 mL | |
| 20 mM | 0.1574 mL | 0.7868 mL | 1.5736 mL | 3.9339 mL | |
| 25 mM | 0.1259 mL | 0.6294 mL | 1.2589 mL | 3.1471 mL | |
| 30 mM | 0.1049 mL | 0.5245 mL | 1.0490 mL | 2.6226 mL | |
| 40 mM | 0.0787 mL | 0.3934 mL | 0.7868 mL | 1.9670 mL | |
| 50 mM | 0.0629 mL | 0.3147 mL | 0.6294 mL | 1.5736 mL | |
| 60 mM | 0.0525 mL | 0.2623 mL | 0.5245 mL | 1.3113 mL | |
| 80 mM | 0.0393 mL | 0.1967 mL | 0.3934 mL | 0.9835 mL | |
| 100 mM | 0.0315 mL | 0.1574 mL | 0.3147 mL | 0.7868 mL |
MO-I-500 Related Classifications
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