Mps1-IN-10
Based on 1 Customer Validation
Mps1-IN-10 (Compound 9) is an inhibitor for Mps1 with an IC50 of 6.4 nM. Mps1-IN-10 inhibits the proliferation of cancer cell MDA-MB-231 with a GI50 of 11 nM. Mps1-IN-10 exhibits anti-tumor efficacy in mice MDA-MB-231 xenograft models.
For research use only. We do not sell to patients.
- Purity: 98.20%
- CAS No.: 2489220-49-5
- Formula: C24H27N7O2
- Molecular Weight:445.52
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
IC50: 6.4 nM (Msp1)
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDA-MB-231 | GI50 |
11 nM
Compound: 9
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Growth inhibition of human MDA-MB-231 cells measured after 5 days by CellTiter-Glo assay
Growth inhibition of human MDA-MB-231 cells measured after 5 days by CellTiter-Glo assay
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[PMID: 33942608] |
Chemical Information
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CAS No. 2489220-49-5
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Appearance Solid
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Molecular Weight 445.52
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Formula C24H27N7O2
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Color White to off-white
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SMILES
N#CC1=CNC2=NC(NC3=CC=C(N4C(CCC4)=O)C=C3OC)=NC(NC5CCCCC5)=C21
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)