MTSSL-15N,d15
MTSSL-15N,d15-1 (Otmpmms-15N,d15) is the deuterium and 15N-labeled MTSSL (HY-130509). MTSSL (Otmpmms) is a highly reactive thiol-specific spin label that can be used to label thiol residues in proteins for the determination of protein structure and dynamics, as well as studies on protein-protein interactions. MTSSL serves as a nitroxide labeling reagent for cysteine residues in recombinant mouse prion protein (moPrPC) mutants. MTSSL can be applied in studies of transmissible spongiform encephalopathies (prion diseases).
For research use only. We do not sell to patients.
- CAS No.: 384342-58-9
- Formula: C10H3D1515NO3S2*
- Molecular Weight:280.47
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 384342-58-9
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Unlabeled Cas 81213-52-7
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Appearance Solid
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Molecular Weight 280.47
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Formula C10H3D1515NO3S2*
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Color Brown to dark brown
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SMILES
[O][15N]1C(C([2H])([2H])[2H])(C(C([2H])(SS(C)(=O)=O)[2H])=C(C1(C([2H])([2H])[2H])C([2H])([2H])[2H])[2H])C([2H])([2H])[2H]
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Synonyms
Otmpmms-15N,d15
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)