Mukonine
Mukonine is a carbazole antitumor and anti-inflammatory compound.
For research use only. We do not sell to patients.
- CAS No.: 23523-94-6
- Formula: C15H13NO3
- Molecular Weight:255.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
43 μM
Compound: mukonine
|
Antiproliferative activity against human HCT116 cells after 72 hrs
Antiproliferative activity against human HCT116 cells after 72 hrs
|
[PMID: 17548198] |
Chemical Information
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CAS No. 23523-94-6
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Molecular Weight 255.27
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Formula C15H13NO3
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SMILES
O=C(C1=CC2=C(NC3=C2C=CC=C3)C(OC)=C1)OC
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Yan Q, et al. A Palladium-Catalyzed Ullmann Cross-Coupling/Reductive Cyclization Route to the Carbazole Natural Products 3-Methyl-9H-carbazole, Glycoborine, Glycozoline, Clauszoline K, Mukonine, and Karapinchamine A. J Org Chem. 2017 Apr 21;82(8):4148-4159. [Content Brief]
[2]. Liger F, et al. Synthesis and antiproliferative activity of clausine E, mukonine, and koenoline bioisosteres. Bioorg Med Chem. 2007 Aug 15;15(16):5615-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)