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Cat. No.: HY-P10410

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AEC5

AEC5 is a Lipopeptoid with antifungal activity against Cryptococcus neoformans. AEC5 has no observable cytotoxicity against human lung, liver, or red blood cells at the MIC value (6.3 μg/mL) for Cryptococcus neoformans.

For research use only. We do not sell to patients.

CAS No.: 2035042-31-8
Formula: C₂₈H₅₁N₅O₄
Molecular Weight:521.74

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

AEC5 Chemical Structure

CAS No.: 2035042-31-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	43.6 μg/mL Compound: AEC5	Cytotoxicity against human HepG2 cells measured after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells measured after 48 hrs by MTT assay	[PMID: 27994753]
NIH3T3	IC₅₀	48.6 μg/mL Compound: AEC5	Cytotoxicity against mouse NIH/3T3 cells measured after 48 hrs by MTT assay Cytotoxicity against mouse NIH/3T3 cells measured after 48 hrs by MTT assay	[PMID: 27994753]

Chemical Information

CAS No. 2035042-31-8
Molecular Weight 521.74
Formula C₂₈H₅₁N₅O₄
Sequence

{Ntri}-{NLys}-{Nfur}
Sequence Shortening

{Ntri}-{NLys}-{Nfur}
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Spicer SK, et al. Toward a clinical antifungal peptoid: Investigations into the therapeutic potential of AEC5. Biopolymers. 2019 Jun;110(6):e23276. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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