ArnicolideC
Based on 1 Customer Validation
ArnicolideC is a sesquiterpene lactone isolated Centipeda minima. ArnicolideC exertes a cytotoxic effect on the panel of Nasopharyngeal carcinoma (NPC) cells, significantly inhibiting cell growth in a dose- and time- dependent manner. ArnicolideC also exhibits inhibitory effects on NPC proliferation.
For research use only. We do not sell to patients.
- Purity: 99.0%
- CAS No.: 34532-67-7
- Formula: C19H26O5
- Molecular Weight:334.41
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Chemical Information
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CAS No. 34532-67-7
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Appearance Solid
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Molecular Weight 334.41
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Formula C19H26O5
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Color White to off-white
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SMILES
CC(C)C(O[C@H]1[C@@]([C@@H]2C)([H])[C@@](OC2=O)([H])C[C@@H](C)[C@@]3([H])[C@]1(C(C=C3)=O)C)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (299.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Chan CO, et al. Qualitative and quantitative analysis of sesquiterpene lactones in Centipeda minima by UPLC-Orbitrap-MS & UPLC-QQQ-MS. J Pharm Biomed Anal. 2019 May 30;174:360-366. [Content Brief]
[2]. Liu R, et al. Arnicolide D, from the herb Centipeda minima, Is a Therapeutic Candidate against Nasopharyngeal Carcinoma. Molecules. 2019 May 17;24(10). [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9903 mL | 14.9517 mL | 29.9034 mL | 74.7585 mL |
| 5 mM | 0.5981 mL | 2.9903 mL | 5.9807 mL | 14.9517 mL | |
| 10 mM | 0.2990 mL | 1.4952 mL | 2.9903 mL | 7.4759 mL | |
| 15 mM | 0.1994 mL | 0.9968 mL | 1.9936 mL | 4.9839 mL | |
| 20 mM | 0.1495 mL | 0.7476 mL | 1.4952 mL | 3.7379 mL | |
| 25 mM | 0.1196 mL | 0.5981 mL | 1.1961 mL | 2.9903 mL | |
| 30 mM | 0.0997 mL | 0.4984 mL | 0.9968 mL | 2.4920 mL | |
| 40 mM | 0.0748 mL | 0.3738 mL | 0.7476 mL | 1.8690 mL | |
| 50 mM | 0.0598 mL | 0.2990 mL | 0.5981 mL | 1.4952 mL | |
| 60 mM | 0.0498 mL | 0.2492 mL | 0.4984 mL | 1.2460 mL | |
| 80 mM | 0.0374 mL | 0.1869 mL | 0.3738 mL | 0.9345 mL | |
| 100 mM | 0.0299 mL | 0.1495 mL | 0.2990 mL | 0.7476 mL |